Extrinsic Apoptosis Reaction Model (EARM)¶
The Extrinsic Apoptosis Reaction Model, or EARM, is a family of models of the extrinsic apoptosis pathway written using the Python software framework PySB. Model variants focus on exploring alternative hypotheses for the mechanism of Mitochondrial Outer Membrane Permeabilization (MOMP), controlled by the Bcl-2 family of proteins.
- Overview of the models
- Implementation details (code and documentation)